8-bromo-adenosine-5'-monophosphate

**8-Bromo-Adenosine‑5′‑Monophosphate** is a synthetic brominated analogue of adenosine monophosphate (AMP), classified as a purine ribonucleoside monophosphate. It is primarily used in research as a molecular probe and tool compound for receptor mapping studies and to investigate nucleotide signaling pathways. The presence of the bromine atom at the C8 position alters its biochemical properties compared to natural AMP. While it can mimic some actions of endogenous AMP in biological systems, it is not approved for therapeutic use and has no established clinical indications. Its mechanism involves acting as an AMP analog; however, specific protein or receptor targets are not well characterized in the literature[1][2][3].

Other names

8-bromoadenosine 5'-monophosphateAdenosine, 8-bromo-, 5'-(dihydrogen phosphate)[(2R,3S,4R,5R)-5-(6-amino–8-bromo–9H-purin–9‑yl)–3,4-dihydroxyoxolan‑2‑yl]methoxy}phosphonic acid