8-bromoadenosine-5'-diphosphate

**8-Bromoadenosine-5'-Diphosphate** is a synthetic, brominated analog of adenosine diphosphate (ADP), belonging to the class of purine ribonucleoside diphosphates. It is primarily used as a biochemical tool in research settings, particularly for receptor mapping studies and as a starting structure for synthesizing other modified ADP derivatives. The introduction of a bromine atom at the eighth position on the adenine ring alters its syn/anti ratio and can affect its interaction with nucleotide-binding proteins or enzymes. There are no known clinical indications or therapeutic uses; it is not approved for medical use and remains an experimental compound[2][4][8].

Other names

8-bromoadenosine 5'-diphosphate8-BrADP8-Bromoadenosine diphosphateC10H14BrN5O10P2 (free acid)CAS 23600-16-0 (free acid)CAS 102185-47-7 (sodium salt)