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9-butyl-8-(4-methoxybenzyl)-9h-purin-6-amine

Development stage
Unknown
Lead developer
Vernalis
Modality
Small Molecules
01

Overview

A synthetic small molecule belonging to the class of 6‑aminopurines, characterized by a butyl group at position 9, a (4‑methoxybenzyl) group at position 8, and an amino group at position 6 on the purine ring. It is an experimental compound with no approved medical indications or marketed formulations. The primary mechanism of action is inhibition of heat shock protein HSP90-alpha (HSP90AA1), a molecular chaperone involved in protein folding and stabilization. By inhibiting HSP90-alpha, this compound may disrupt cellular stress responses and has been investigated as a research tool for studying chaperone biology[1][3][7]. No clinical trials or therapeutic uses are reported.

Other names
9-butyl-8-(4-methoxybenzyl)-9H-purin-6-aminoPurine-Based Inhibitor 2
02

Targets

HSP90AA1 (Heat shock protein HSP90-alpha)

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