9-hydroxy-8-methoxy-6-nitro-phenanthrol[3,4-d][1,3]dioxole-5-carboxylic acid

This compound is a synthetic or naturally occurring small molecule belonging to the class of aristolochic acids and derivatives. It is structurally related to other aristolochic acids found in plants of the Aristolochia genus. The molecule features a phenanthrene core with hydroxy, methoxy, nitro substituents and a dioxole ring fused to the structure. It has been identified as an experimental compound with no current approved medical use. Aristolochic acids are known for their nephrotoxic and carcinogenic properties; they act primarily by forming DNA adducts that can lead to mutations and cancer development. This specific derivative may have similar biological activities but is not used therapeutically due to toxicity concerns[1][2][7].

Other names

9-hydroxy aristolochic acidPhenanthro[3,4-d]-1,3-dioxole-5-carboxylicacid, 9-hydroxy-8-methoxy-6-nitro-Aristolochic acid VIIaHY-N2012HY-N-2012HY-N 2012