Drug intelligence / Profile preview

A + fish oil

Development stage
Unknown
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Oral
01

Overview

The term **A + fish oil** is a non-specific designation that typically refers to a combination of Vitamin A (retinol or its derivatives) and fish oil, which is a source of omega-3 fatty acids such as eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). This combination is most frequently encountered in the context of dietary supplements, particularly cod liver oil, which naturally contains high concentrations of both Vitamin A and omega-3 fatty acids. Vitamin A is essential for vision, immune function, and cellular communication, while fish oil is utilized for its cardiovascular benefits and anti-inflammatory properties. Alternatively, in certain clinical research contexts, 'A' may serve as a shorthand for aspirin (acetylsalicylic acid), and the combination is studied for its synergistic effects on inflammatory resolution through the production of aspirin-triggered resolvins. However, 'A' is not a recognized canonical name, sponsor development code, or brand name for a specific pharmaceutical agent.

Other names
A + fish oil
02

Targets

LTCC (Voltage-gated calcium channel (L-type))FFAR4 (Free fatty acid receptor 4)NaV (Voltage-gated sodium channels)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)DGAT2 (Hepatic diacylglycerol acyltransferase 2)

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