aceclofenac + paracetamol + chlorzoxazone

Aceclofenac + paracetamol + chlorzoxazone is a fixed-dose combination (FDC) medication developed by Kriam Pharma for the symptomatic treatment of painful muscle spasms associated with musculoskeletal conditions. Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID) that works by inhibiting the cyclooxygenase-2 (COX-2) enzyme, thereby reducing the production of prostaglandins that cause pain and inflammation. Paracetamol acts as an additional analgesic and antipyretic, likely through the inhibition of prostaglandin synthesis in the central nervous system. Chlorzoxazone is a centrally acting skeletal muscle relaxant that inhibits multi-synaptic reflex arcs at the level of the spinal cord and subcortical areas of the brain, leading to muscle relaxation. This oral combination is typically used for conditions such as low back pain, sprains, and strains where both pain and muscle tension are present.

Brand names

KRIAM-MR

Other names

Aceclofenac, Paracetamol, and Chlorzoxazone Tablets