Drug intelligence / Profile preview

acetaminophen + chlorphenamine + artificial bezoar

Development stage
Unknown
Lead developer
China Resources Sanjiu Medical & Pharmaceutical
Modality
Small Molecules
Administration
Oral
01

Overview

This is a fixed-dose combination pediatric medication containing acetaminophen (paracetamol), chlorphenamine maleate, and artificial bezoar. It is primarily used to relieve symptoms associated with the common cold and influenza in children, such as fever, headache, myalgia, sneezing, rhinorrhea, nasal congestion, and sore throat. - **Acetaminophen** acts as an analgesic and antipyretic by inhibiting prostaglandin synthesis in the central nervous system. - **Chlorphenamine maleate** is a first-generation antihistamine that antagonizes histamine H1 receptors to reduce allergic symptoms like sneezing and runny nose. - **Artificial bezoar** (artificial Calculus Bovis) is included for its traditional use in Chinese medicine for its purported anti-inflammatory and detoxifying effects; it contains bilirubin as an active component[1][4][5][6].

Brand names
小儿氨酚黄那敏颗粒
Other names
Pediatric Paracetamol, Artificial Cow-bezoar and Chlorphenamine Maleate GranulesXiao’er Anfen Huang Namin Keli小儿氨酚黄那敏
02

Targets

HRH1 (Histamine H1 Receptor)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)

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