acetaminophen + codeine + caffeine

Acetaminophen + codeine + caffeine is a fixed-dose combination oral analgesic containing three active ingredients: - **Acetaminophen** (also known as paracetamol) is an analgesic and antipyretic that works by inhibiting prostaglandin synthesis in the central nervous system to reduce pain and fever. - **Codeine** is an opioid agonist that acts primarily on the mu-opioid receptor in the brain and spinal cord to provide pain relief through inhibition of ascending pain pathways. - **Caffeine** is a central nervous system stimulant that enhances the analgesic effect of acetaminophen and counteracts drowsiness caused by codeine. This combination is used for short-term relief of mild to moderate pain when other non-opioid treatments are inadequate or not tolerated. Caffeine may also help improve alertness and increase the effectiveness of analgesics[8]. The product carries risks associated with opioids (addiction, abuse, misuse), hepatotoxicity from excessive acetaminophen use, and potential side effects from caffeine such as insomnia or palpitations.

Brand names

Tylenol No. 3Tylenol No. 4ACETAMINOPHEN WITH CODEINE – CAPLET

Other names

acetaminophen/codeine/caffeineparacetamol/codeine/caffeine