Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
acetaminophen + ibuprofen + caffeine
- Development stage
- Phase 2
- Lead developer
- AdvaCare Pharma
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
A combination pharmaceutical product containing **acetaminophen** (also known as paracetamol), **ibuprofen**, and **caffeine**. Acetaminophen acts as an analgesic and antipyretic, reducing pain and fever. Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) with analgesic, anti-inflammatory, and antipyretic effects. Caffeine, a methylxanthine stimulant, enhances the analgesic efficacy of acetaminophen and ibuprofen when used as an adjuvant. This combination is formulated for the short-term relief of mild-to-moderate pain, inflammation, and fever, and is indicated for conditions such as headache (including tension and migraine), arthritis, toothache, and primary dysmenorrhea[1].
- Brand names
- TriRelief
- Other names
- paracetamol + ibuprofen + caffeine
02
Targets
ADORA2A (Adenosine A₂A Receptor)ADORA3 (Adenosine A3 receptor)ADORA1 (Adenosine receptor A1 subtype)ADORA2B (Adenosine A2B receptor)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)PGHS-1 (Prostaglandin G/H Synthase 1)
Beyond the preview
Go deeper on acetaminophen + ibuprofen + caffeine.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on acetaminophen + ibuprofen + caffeine.