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Drug intelligence / Profile preview
acetaminophen + phenylephrine
- Development stage
- Phase 1
- Lead developer
- CRIS Pharma
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Acetaminophen + Phenylephrine is an approved, orally administered small molecule combination drug. It contains two active ingredients: acetaminophen (paracetamol), an analgesic and antipyretic that works centrally to reduce pain and fever, and phenylephrine, a sympathomimetic decongestant that acts as an alpha-1 adrenergic receptor agonist to relieve nasal and sinus congestion. Together, the combination is used to treat symptoms associated with the common cold, flu, and upper respiratory conditions, including pain, fever, and nasal congestion. The drug is typically administered in tablet form and is widely available as a generic formulation.
- Brand names
- Flusip COLD & FLU
- Other names
- Paracetamol with Phenylephrine Tabletsacetaminophen and phenylephrine
02
Targets
PGHS-1 (Prostaglandin G/H Synthase 1)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)ADRA1A (α1A)ADRA1B (α1B)ADRA1D (α1D)
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