Drug intelligence / Profile preview

acetate ringer's solution

Development stage
Unknown
Lead developer
Nagoya City University
Modality
Small Molecules
Administration
Intravenous
01

Overview

Acetate Ringer's solution (1% glucose) is an intravenous crystalloid solution used perioperatively, particularly in women undergoing cesarean section. It is a balanced electrolyte solution containing sodium, potassium, calcium, and chloride, with acetate serving as a buffering agent that is metabolized to bicarbonate in the body. The inclusion of 1% glucose (dextrose) provides a metabolic substrate intended to maintain blood glucose homeostasis in both the mother and the neonate. This specific concentration aims to prevent neonatal hypoglycemia while avoiding the risks of maternal or fetal hyperglycemia associated with higher glucose concentrations (e.g., 5%). It is primarily used for fluid replacement and electrolyte maintenance during surgical procedures.

Other names
Ringer's acetate solutionglucose-containing acetate Ringer's solution1% glucose acetate Ringer's solution
02

Targets

ClC (CLC chloride channel family)

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