Drug intelligence / Profile preview

acetate Ringer's solution (Hebei Children's Hospital)

Development stage
Unknown
Lead developer
Hebei Children's Hospital
Modality
Small Molecules
Administration
Intravenous
01

Overview

Acetate Ringer's solution is a balanced crystalloid intravenous fluid used for fluid resuscitation and perioperative maintenance. It contains electrolytes (sodium, potassium, calcium, magnesium, and chloride) in concentrations similar to extracellular fluid, with sodium acetate serving as a buffering agent. Unlike Lactated Ringer's solution, which relies on hepatic metabolism of lactate to bicarbonate, acetate is metabolized to bicarbonate in various tissues, including skeletal muscle. This makes acetate Ringer's particularly suitable for patients with impaired liver function, such as infants with biliary atresia undergoing the Kasai procedure. It helps maintain acid-base balance and intravascular volume while minimizing the risk of hyperchloremic acidosis associated with normal saline.

Brand names
Physio140Physio-140Physio 140Ringer-AcetateSterofundin ISO
Other names
Ringer-acetate solutionAcetated Ringer's solution
02

Targets

ClC (CLC chloride channel family)

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