acetated Ringer's solution

Acetated Ringer's solution is a balanced isotonic crystalloid solution used for intravenous fluid replacement and volume expansion. It contains a specific mixture of electrolytes—sodium, potassium, calcium, and chloride—along with sodium acetate, which serves as a buffering agent. Unlike lactate-based solutions, acetate is rapidly metabolized in various tissues, including skeletal muscle, into bicarbonate, making it an effective buffer for maintaining acid-base balance even in patients with impaired liver function. In the clinical research context of Sodertalje Hospital, the solution is utilized to study volume kinetics, a mathematical modeling technique that tracks changes in blood hemoglobin concentration to determine fluid distribution and elimination rates. This research specifically evaluates how the elimination of the infused fluid is retarded in dehydrated subjects, potentially providing a new method for detecting and quantifying dehydration.

Brand names

Ringer-Acetat

Other names

Ringer's acetateAcetated Ringer's