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acetylsalicylic acid + caffeine
- Development stage
- Unknown
- Lead developer
- CAPS Holdings
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Mr Strong Capsules is an over-the-counter (OTC) oral combination analgesic developed and manufactured by CAPS Holdings in Zimbabwe. It is formulated as a capsule containing 500 mg of acetylsalicylic acid (aspirin) and caffeine. The combination is indicated for the fast-acting relief of mild to moderate pain, including headaches, and for the symptomatic treatment of colds, flu, and sore throat. Acetylsalicylic acid acts as a nonsteroidal anti-inflammatory drug (NSAID) by inhibiting cyclooxygenase (COX) enzymes to reduce pain, fever, and inflammation, while caffeine acts as an adjuvant stimulant that blocks adenosine receptors, enhancing the analgesic efficacy of the NSAID.
- Brand names
- Mr Strong CapsulesMr. Strong Capsules
- Other names
- acetylsalicylic acid + caffeineaspirin + caffeine
02
Targets
ADORA2A (Adenosine A₂A Receptor)ADORA1 (Adenosine receptor A1 subtype)ADORA3 (Adenosine A3 receptor)PGHS-1 (Prostaglandin G/H Synthase 1)ADORA2B (Adenosine A2B receptor)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)
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