acetylsalicylic acid + calcium carbonate

Acetylsalicylic acid + calcium carbonate is a fixed-dose combination of two active ingredients. Acetylsalicylic acid (commonly known as aspirin) is a non-selective cyclooxygenase (COX) inhibitor that provides analgesic, antipyretic, anti-inflammatory effects and irreversibly inhibits platelet aggregation by blocking COX-1 and COX-2 enzymes. This action reduces the synthesis of prostaglandins and thromboxane A2, leading to pain relief and prevention of blood clots[3][4]. Calcium carbonate acts as an antacid by neutralizing gastric hydrochloric acid and increasing gastric pH; it also serves as a dietary calcium supplement[5][7]. The combination is used for the treatment of mild to moderate pain, fever, inflammatory conditions such as arthritis, prevention of heart attack or stroke due to its antiplatelet effect (from aspirin), while the addition of calcium carbonate helps reduce gastrointestinal irritation caused by aspirin[1][2].

Brand names

MagnaprinAspirin BufferedArthritis Pain FormulaAspir-Mox

Other names

aspirin + calcium carbonate