Drug intelligence / Profile preview

activated charcoal + papaverine

Development stage
Unknown
Lead developer
Laboratoires Elerté
Modality
Small Molecules
Administration
Oral
01

Overview

Acticarbine is a fixed-dose combination medication developed by Laboratoires Élerté for the symptomatic treatment of functional digestive disorders, particularly those characterized by intestinal bloating and flatulence. It consists of activated charcoal and papaverine hydrochloride. Activated charcoal serves as a potent adsorbent, binding intestinal gases, toxins, and bacteria to reduce abdominal distension and alleviate discomfort. Papaverine is a musculotropic antispasmodic that acts directly on the smooth muscles of the gastrointestinal tract, likely through the inhibition of phosphodiesterases and the modulation of calcium channels, thereby relieving cramps and spasms. The product is approved and marketed in several regions, including France, for adult use in managing transit disorders associated with meteorism.

Brand names
Acticarbine
Other names
Acticarbine Élerté
02

Targets

CACNA1C (Voltage-dependent L-type calcium channel subunit alpha-1C)PDE (Phosphodiesterase family)

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