Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
Adductor Canal Block-University Health Network, Toronto-postoperative pain refers to a specific regional anesthesia protocol developed and evaluated by the University Health Network (UHN) in Toronto for the management of postoperative pain following total knee arthroplasty (TKA). The intervention primarily involves the administration of a local anesthetic solution, typically ropivacaine (0.5%) combined with epinephrine (1:400,000), into the adductor canal to target the saphenous nerve. This technique is designed to provide sensory blockade while sparing the motor function of the quadriceps muscle, thereby facilitating earlier functional recovery and mobilization compared to traditional femoral nerve blocks. In the specific clinical trial context (NCT02414152), this block was administered in conjunction with spinal anesthesia using bupivacaine, with some study arms also receiving intrathecal morphine to enhance analgesic efficacy.
Beyond the preview
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Follow clinical development from study design and recruitment through results.
Explore development by indication, patient population, and geography.
Trace asset ownership, licensing agreements, and commercial partnerships.
Explore the patent landscape and regulatory exclusivity around an asset.
Compare development programs by target, modality, and indication.
Connect source evidence and development news to your research questions.
See how Gosset can support your research on Adductor Canal Block-University Health Network, Toronto-postoperative pain.