Drug intelligence / Profile preview

adenovirus type 4 vaccine, live + adenovirus type 7 vaccine, live

Development stage
Approved
Lead developer
Teva Pharmaceutical Industries
Modality
Vaccines & Immunotherapeutics
Administration
Oral
01

Overview

Adenovirus type 4 vaccine, live + adenovirus type 7 vaccine, live is an **oral live biologic vaccine** for active immunization against febrile acute respiratory disease caused by **adenovirus serotypes 4 and 7**. It was originally developed and manufactured by **Barr** and later approved in the United States in 2011, with current marketing by **Teva**. The product is formulated as **two enteric-coated tablets**, one containing live adenovirus type 4 and one containing live adenovirus type 7, which are swallowed whole. The vaccine replicates in the **intestinal tract** rather than the respiratory tract, inducing protective immunity that helps prevent disease from wild-type adenovirus 4 and 7. It is specifically approved for **military personnel aged 17 through 50 years**, particularly recruits in basic training, and vaccinated individuals may shed live vaccine virus in stool for up to 28 days after administration.

Brand names
Adenovirus Vaccine Live Oral
Other names
adenovirus vaccine live oral type 4 and type 7live oral adenovirus type 4 and type 7 vaccine
02

Targets

CXADR (Coxsackievirus and adenovirus receptor)

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