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adipose-derived mesenchymal stem cells (Peking University People's Hospital)
- Development stage
- Unknown
- Lead developer
- Peking University People's Hospital
- Modality
- Stem Cell Therapies → Cell Therapies
- Administration
- Intraarticular
01
Overview
Adipose-derived mesenchymal stem cells (AD-MSCs) are a type of multipotent cell therapy being developed by Peking University People's Hospital for the treatment of knee osteoarthritis. These cells are isolated from adipose tissue and administered via intra-articular injection. The therapeutic mechanism involves the secretion of various bioactive molecules (the secretome) that possess anti-inflammatory, immunomodulatory, and chondroprotective properties. By modulating the joint's microenvironment, AD-MSCs aim to reduce pain, improve physical function, and potentially facilitate the repair of damaged articular cartilage in patients with osteoarthritis. The specific clinical program at Peking University People's Hospital has evaluated these cells in randomized trials comparing their efficacy and safety against standard treatments like hyaluronic acid.
- Other names
- AD-MSCsAdipose-derived MSCsMesenchymal Stem Cells from adipose
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