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adsorbed diphtheria toxoid + inactivated poliovirus vaccine
- Development stage
- Unknown
- Lead developer
- Sichuan Provincial Center for Disease Control and Prevention
- Modality
- Vaccines & Immunotherapeutics
- Administration
- Intramuscular
01
Overview
Adsorbed diphtheria toxoid + inactivated poliovirus vaccine is an investigational combination vaccine developed by the Sichuan Provincial Center for Disease Control and Prevention in China. It is a biologic vaccine containing adsorbed diphtheria toxoid and inactivated poliovirus (IPV) types 1, 2, and 3 as its active components. The vaccine is designed to elicit protective antibody responses against diphtheria and poliomyelitis. It is currently being evaluated in Phase I clinical trials in China to assess its safety and immunogenicity in infants (2–24 months) and children (4–6 years), often compared against standard DTaP-IPV or DTaP-IPV-Hib combination vaccines. The biological targets are the diphtheria toxin (neutralized by anti-diphtheria toxoid antibodies) and poliovirus types 1, 2, and 3 (neutralized by anti-poliovirus antibodies).
- Other names
- adsorbed acellular diphtheria inactivated poliomyelitis combined vaccineadsorbed acellular diphtheria inactivated poliomyelitis vaccine
02
Targets
γδ TCR (T-cell receptor)BCR (Immunoglobulin G B Cell Receptor)
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