Drug intelligence / Profile preview

albendazole + praziquantel

Development stage
Unknown
Lead developer
GSK
Modality
Small Molecules
Administration
Oral
01

Overview

A combination antiparasitic therapy consisting of albendazole and praziquantel. This combination leverages the complementary mechanisms of both drugs to achieve improved efficacy against various parasitic infections, particularly neurocysticercosis and hydatidosis (echinococcosis). Studies have shown that this combination is more effective in destroying viable brain cysts in neurocysticercosis than albendazole alone.

Other names
albendazole and praziquantelpraziquantel and albendazole
02

Targets

TUBB (Tubulin (alpha and beta subunits))CaV (Voltage-gated calcium channel protein complex)

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