albumin + electrolyte solution

Albumin + electrolyte solution refers to a fluid resuscitation regimen being evaluated for the treatment of sepsis-induced hypotension in patients with cirrhosis and acute-on-chronic liver failure (ACLF). This intervention, specifically studied at the Post Graduate Institute of Medical Education and Research, Chandigarh, involves the administration of 20% human albumin (at doses of 0.5-1 g/kg) in conjunction with balanced salt solutions (such as Plasmalyte). Albumin acts as a colloid to increase plasma oncotic pressure and expand intravascular volume, while the electrolyte solution provides crystalloid-based volume replacement and maintains acid-base balance. The regimen aims to improve hemodynamic stability and fluid responsiveness in critically ill liver disease patients, who often exhibit baseline hypoalbuminemia and altered hemodynamics.

Other names

20% albumin and balanced salt solutionalbumin and plasmalyte