Drug intelligence / Profile preview

albuterol + budesonide + formoterol

Development stage
Preclinical
Lead developer
AstraZeneca
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
Administration
Inhalation
01

Overview

This is a combination drug consisting of three active ingredients—albuterol, budesonide, and formoterol—delivered via inhalation. Albuterol is a short-acting beta-2 adrenergic agonist (SABA) that acts as a bronchodilator to quickly relax airway smooth muscle and relieve acute bronchospasm. Budesonide is an inhaled corticosteroid (ICS) that reduces inflammation in the airways, helping to prevent asthma attacks and control chronic symptoms. Formoterol is a long-acting beta-2 adrenergic agonist (LABA), providing prolonged bronchodilation for maintenance therapy in asthma or chronic obstructive pulmonary disease (COPD). The combination aims to provide both rapid symptom relief and ongoing anti-inflammatory control for respiratory diseases such as asthma or COPD.

02

Targets

GR (Glucocorticoid receptor)ADRB2 (β2)

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