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aldosterone (targeted delivery)

Development stage: Preclinical
Lead developer: PIF Partners
Modality: Targeted Liposomes → Liposomes → Lipid-based Nanoparticles → Nanoparticles → Drug Delivery Systems, Small Molecules

Overview

aldosterone (targeted delivery) is a preclinical-stage therapeutic candidate being developed by PIF Partners. It utilizes a proprietary platform technology designed to deliver aldosterone specifically to activated macrophages. By targeting these cells, the drug aims to modulate macrophage-mediated inflammatory responses while potentially minimizing systemic side effects associated with mineralocorticoid receptor activation in other tissues. The development is currently in the preclinical phase, with no specific indications disclosed beyond the general targeting of activated macrophages.

Other names: aldosterone-PIF Partners-activated macrophages-targeted delivery

Targets

GPER1 (G protein-coupled estrogen receptor 1)MR (Mineralocorticoid receptor)

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