aliskiren + hydrochlorothiazide

Aliskiren + hydrochlorothiazide is an oral fixed-dose antihypertensive combination marketed as **Tekturna HCT** and other regional brands. It combines aliskiren, a nonpeptide direct renin inhibitor that suppresses renin activity and downstream angiotensin generation, with hydrochlorothiazide, a thiazide diuretic that promotes renal sodium and water excretion. The complementary mechanisms provide additive blood-pressure lowering and are approved for treatment of hypertension, including use when monotherapy is insufficient and as initial therapy in patients likely to require more than one antihypertensive agent.

Brand names

Co-RasilezCo-TekturnaRasilez HCTTekturna HCT

Other names

aliskiren + HCTZaliskiren + hydrochlorothiazidealiskiren hydrochlorothiazidealiskiren/hydrochlorothiazidehydrochlorothiazide + aliskiren