allantoin + coal tar + clioquinol

**Allantoin + coal tar + clioquinol** is a topical pharmaceutical combination developed primarily for the treatment of dermatological conditions associated with scaling, inflammation, and microbial involvement, such as psoriasis and seborrheic dermatitis. - **Allantoin** acts as a skin protectant and keratoplastic, promoting skin healing and normal keratinization. - **Coal tar** is a keratolytic agent that reduces scaling, itching, and inflammation by suppressing DNA synthesis and retarding cell proliferation in hyperactive skin. - **Clioquinol** serves as an antimicrobial, targeting potential secondary infections by inhibiting the growth of bacteria and fungi. The combination can be formulated as a shampoo or lotion and may include additional agents such as triclosan. A notable marketed product is Sebryl Plus. Clinical evidence and patents support its effectiveness in rapidly reducing scaling and redness in psoriasis and related dermatoses[1][4][5].