Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
allogeneic human mesenchymal stem cells (University of Miami Miller School of Medicine)
- Development stage
- Unknown
- Lead developer
- University of Miami Miller School of Medicine
- Modality
- Stem Cell Therapies → Cell Therapies
- Administration
- Intravenous
01
Overview
Allogeneic human mesenchymal stem cells (allo-hMSCs) are a biologic cell therapy being investigated for the treatment of comorbid Alcohol Use Disorder (AUD) and Major Depressive Disorder (MDD). This specific application, pioneered by Dr. Ihsan M. Salloum at the University of Miami Miller School of Medicine, is based on the hypothesis that chronic inflammation is a key driver of treatment resistance and symptom severity in patients with both conditions. The therapy involves a single intravenous infusion of 100 million allogeneic MSCs, which are intended to exert potent anti-inflammatory and immunomodulatory effects. By reducing systemic and neuro-inflammation, the treatment aims to improve clinical outcomes in this difficult-to-treat population. The Phase I/II ALAUNUS trial evaluated the safety and efficacy of this approach.
- Other names
- allogeneic human mesenchymal stem cell therapyALAUNUS trial stem cells
Beyond the preview
Go deeper on allogeneic human mesenchymal stem cells (University of Miami Miller School of Medicine).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on allogeneic human mesenchymal stem cells (University of Miami Miller School of Medicine).