allogeneic pancreatic islet cells (Baylor Research Institute)

Allogeneic pancreatic islet cells developed by the Baylor Research Institute are a cell therapy intended for the treatment of type 1 diabetes mellitus. The therapy involves the enzymatic isolation of islets of Langerhans from a cadaveric donor pancreas. These islets are then transplanted into the recipient's liver via percutaneous catheterization of the portal venous system. Once engrafted, the islets function to produce insulin in response to blood glucose levels, potentially restoring euglycemia and reducing or eliminating the need for exogenous insulin. The Baylor Research Institute's specific approach focuses on optimizing islet quality through remote site processing, culture techniques, and novel immunosuppression protocols to improve engraftment and long-term survival of the transplanted cells.

Other names

allogeneic islet transplantationislet cell transplantationallogenic pancreatic islet cell transplantation