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aloe vera + probiotic ferment

Development stage: Unknown
Lead developer: Affiliated Stomatological Hospital of Nanchang University
Modality: Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Classical Binding Small Molecules → Small Molecules
Administration: Oral

Overview

aloe vera + probiotic ferment is an investigational combination therapy being evaluated for the treatment of periodontitis. It consists of *Aloe vera* (Aloe barbadensis) extract that has undergone fermentation by specific probiotic strains. This fermentation process is hypothesized to increase the bioavailability and concentration of bioactive compounds, such as acemannan and various polyphenols, which possess anti-inflammatory and antimicrobial properties. In clinical studies, it is typically administered as a periodontal pocket irrigation solution following basic periodontal treatment (scaling and root planing) to modulate the subgingival microbiome and promote tissue healing.

Other names: aloe vera fermentationaloe vera probiotic ferment

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