Drug intelligence / Profile preview

aloe vera + tocopherol + zinc oxide

Development stage
Unknown
Lead developer
Johnson & Johnson
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Topical
01

Overview

This combination is a topical therapeutic used primarily for the prevention and treatment of diaper rash and other minor skin irritations. Zinc oxide serves as the primary active ingredient, acting as a physical barrier (skin protectant) that shields the skin from moisture, enzymes, and fecal matter. Tocopherol (Vitamin E) is included for its antioxidant properties, which help mitigate oxidative stress and support skin integrity. Aloe vera provides emollient and anti-inflammatory effects, soothing the skin and promoting hydration. The combination is widely available in over-the-counter (OTC) creams and ointments.

Brand names
Desitin Daily DefenseBalmexAngel of Mine Diaper Rash Ointment
Other names
aloe vera + vitamin E + zinc oxide

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