aloe vera gel (Oxford Dental College)

Aloe vera gel is a topical botanical preparation derived from the *Aloe vera* plant, utilized for its immunomodulatory, anti-inflammatory, antioxidant, and wound-healing properties. In clinical research conducted by The Oxford Dental College, Hospital and Research Center in Bangalore, India, it has been investigated as a treatment for oral submucous fibrosis (OSMF), a chronic condition often caused by areca nut use that carries a high risk of malignancy. The therapeutic regimen evaluated in Phase 3 trials typically involves the topical application of the gel to oral lesions (approximately 5mg per application) in combination with the oral ingestion of aloe vera juice (30ml twice daily). The preparation aims to alleviate symptoms such as burning sensations and to improve oral mobility, including mouth opening, cheek flexibility, and tongue protrusion, by targeting inflammatory and oxidative pathways.

Other names

aloe vera juicealoe barbadensis gelaloe vera extract