alpha blocker + 5-alpha reductase inhibitor

Alpha blocker + 5-alpha reductase inhibitor is a combination therapy used primarily for the treatment of benign prostatic hyperplasia (BPH). This combination works through complementary mechanisms: alpha blockers relax the muscles around the bladder and prostate to improve urine flow and provide quick symptom relief, while 5-alpha reductase inhibitors reduce prostate size over time by inhibiting the conversion of testosterone to dihydrotestosterone. Clinical studies have demonstrated that this combination therapy is more effective than either medication alone in reducing lower urinary tract symptoms (LUTS), decreasing total prostate volume (TPV), and reducing the risk of disease progression including acute urinary retention and need for BPH-related surgery.

Brand names

Jalyn

Other names

combination therapy for BPH