Drug intelligence / Profile preview

alpha-ketoanalogues + essential amino acids

Development stage
Unknown
Lead developer
Biokindle Lifesciences
Modality
Small Molecules
Administration
Oral
01

Overview

Ketograce is a nutritional supplement containing a combination of alpha-ketoanalogues and essential amino acids, developed by Biokindle Lifesciences for the management of chronic kidney disease (CKD). The product is designed to provide essential amino acids while minimizing nitrogen intake. By providing nitrogen-free keto-precursors that can be transaminated into their corresponding essential amino acids using nitrogen from non-essential amino acids or urea, it helps reduce the accumulation of nitrogenous waste products in the blood. This metabolic shift helps alleviate uremic symptoms, maintain nutritional status, and potentially delay the progression of renal failure and the need for dialysis in patients with stage 3 to 5 CKD.

Brand names
Ketograce
Other names
Alpha ketoanalogue and essential amino acid tablet

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