Alpha-Ribazole-5'-Phosphate Derivative

Alpha-Ribazole-5'-Phosphate Derivative, also known as alpha-Ribazole 5'-phosphate, is a chemical compound classified as a ribose monophosphate, a 1-ribosylbenzimidazole, and a dimethylbenzimidazole. It serves as a metabolite in organisms such as *Escherichia coli* and mice. This compound plays a crucial role as an intermediate in the biosynthetic pathway of cobalamin (vitamin B12) in bacteria, specifically within the nucleotide loop assembly pathway. It is formed through the activation of 5,6-dimethylbenzimidazole (DMB) into its alpha ribotide, a reaction catalyzed by phosphoribosyltransferase. While primarily a biochemical intermediate, it has been identified as a drug candidate with experimental status and is listed within pharmaceutical databases, suggesting potential therapeutic interest or its role as a component in drug-related research.

Other names

ALPHA-RIBAZOLE-5'-PHOSPHATE DERIVATIVEalpha-Ribazole 5'-phosphate(((2R,3S,4R,5S)-5-(1H-1,3-benzodiazol-1-yl)-3,4-dihydroxyoxolan-2-yl)methoxy)phosphonic acidN(1)-(5-Phosphoribosyl)-5,6-dimethylbenzimidazoleDB03079DB-03079DB 03079DB02030DB-02030DB 02030CHEBI:16837975-91-7TT4G266KJNTT-4G266KJNTT 4G266KJNPD060152PD-060152PD 060152