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alprazolam + propranolol
- Development stage
- Unknown
- Lead developer
- Zoic Lifesciences
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
2 CALM TAB is a fixed-dose combination pharmaceutical product containing alprazolam and propranolol hydrochloride. Alprazolam is a benzodiazepine that functions as a positive allosteric modulator of the GABA-A receptor, enhancing the inhibitory effects of gamma-aminobutyric acid (GABA) in the central nervous system to provide anxiolytic, sedative, and muscle relaxant properties. Propranolol is a non-selective beta-adrenergic receptor antagonist that blocks the action of epinephrine and norepinephrine on both beta-1 and beta-2 receptors, thereby reducing the peripheral physical symptoms of anxiety such as tachycardia, tremors, and palpitations. This combination is marketed by Zoic Lifesciences, a generic pharmaceutical company based in India, and is typically indicated for the management of anxiety disorders, particularly when autonomic symptoms are prominent.
- Brand names
- 2 CALM TAB
- Other names
- Alprazolam & Propranolol HCl TabletsAlprazolam and Propranolol hydrochloride
02
Targets
ADRB2 (β2)GABRR (GABA-A receptor subunit rho)ADRB3 (β3)ADRB1 (β1)
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