AM3 + hesperidin + spermidine

AM3 + hesperidin + spermidine is a multi-ingredient dietary supplement blend investigated for its potential to modulate immune function and reverse biological aging. The combination consists of three active components: AM3 (a natural glycophosphopeptical compound derived from *Candida albicans*), hesperidin (a citrus-derived flavonoid), and spermidine (a naturally occurring polyamine). AM3 is the active principle of the commercial immunomodulatory product Inmunoferon, known for its ability to regulate immune responses. Hesperidin provides antioxidant and anti-inflammatory benefits, while spermidine is recognized for its role in inducing autophagy and promoting cellular longevity. A randomized controlled trial conducted by researchers at the Complutense University of Madrid (NCT06249620) demonstrated that daily supplementation with this blend significantly reduced biological age, as measured by the Immunity Clock model, and improved oxidative-inflammatory status in healthy adults.

Other names

AM3/hesperidin/spermidine combinationAM3 + hesperidin + spermidine