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American ginseng root + polysaccharides is a combination dietary supplement derived from the roots of *Panax quinquefolius* (American ginseng) and its bioactive polysaccharide components. American ginseng contains several active ingredients, primarily ginsenosides and various plant-derived polysaccharides. The combination is used for its adaptogenic and immunomodulatory properties, with evidence suggesting synergistic effects on immune function, gut barrier integrity, and microbiome composition. Mechanistically, the supplement modulates immune responses by influencing lymphocyte subsets (notably CD4+ T cells), stimulating IgA-secreting cells in the intestine, enhancing tight junction protein expression in gut epithelium (e.g., ZO-1, occludin), and restoring beneficial gut microbiota while reducing harmful bacteria. It has been studied for use in conditions such as chemotherapy-induced immunosuppression and intestinal mucosal damage[5][6]. The product is available as a nutraceutical or dietary supplement rather than a regulated pharmaceutical drug.
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