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aminophylline + chlorpheniramine + methoxyphenamine + noscapine
- Development stage
- Unknown
- Lead developer
- Shanghai Sine
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Nuoertong Compound Methoxyphenamine Capsules is a fixed-dose combination drug containing aminophylline, chlorpheniramine, methoxyphenamine, and noscapine. It is widely used in China for the treatment of bronchial asthma, asthmatic bronchitis, and coughs associated with other respiratory tract disorders. Methoxyphenamine is a beta-adrenergic receptor agonist that relaxes bronchial smooth muscle. Aminophylline acts as a phosphodiesterase inhibitor and adenosine receptor antagonist to promote bronchodilation and reduce mucosal edema. Noscapine is a non-narcotic cough suppressant that acts centrally to inhibit the cough reflex, while chlorpheniramine is an H1-antihistamine that reduces allergic symptoms and airway inflammation. The combination is marketed under the brand name Nuoertong by Shanghai Yan'an Pharmaceutical and Shanghai Sine Pharmaceutical.
- Brand names
- AsmetonKezhiNuoertong
- Other names
- Compound MethoxyphenamineCompound Methoxyphenamine Capsulesaminophylline + chlorpheniramine maleate + methoxyphenamine hydrochloride + noscapine复方甲氧那明复方甲氧那明胶囊
02
Targets
ADRB2 (β2)HRH1 (Histamine H1 Receptor)SIGMAR1 (Sigma non-opioid intracellular receptor 1)PDE (Phosphodiesterase family)ADOR (Adenosine receptors)
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