Drug intelligence / Profile preview

amitraz + cypermethrin

Development stage
Unknown
Lead developer
Pure Med Farma
Modality
Small Molecules
Administration
Topical
01

Overview

Amitick C Solution is a veterinary ectoparasiticide developed and marketed by Pure Med Farma (Pure Med Biotech). It is a combination product typically formulated for the control and treatment of external parasites such as ticks, mites, lice, and fleas in livestock (cattle, sheep, goats) and dogs. The solution contains two primary active ingredients: amitraz and cypermethrin. Amitraz is a formamidine acaricide and insecticide that acts as an agonist at octopamine receptors in the parasite's nervous system, leading to overexcitation and death. Cypermethrin is a synthetic pyrethroid that disrupts the nervous system by modulating voltage-gated sodium channels, preventing their closure and causing prolonged nerve impulses that result in paralysis. The product is intended for topical administration, often applied as a spray or dip.

Brand names
Amitick C Solution
Other names
Amitick CAmitraz and Cypermethrin Solution
02

Targets

NaV (Voltage-gated sodium channels)ADRA2 (Alpha-2 adrenergic receptor family)Octβ2R (Varroa destructor octopamine receptor beta-2)OAR (Octopamine receptor)

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