amlodipine + levosulpiride

**Amlodipine + levosulpiride** is a fixed-dose combination drug containing two active pharmaceutical ingredients: amlodipine, a dihydropyridine calcium channel blocker used primarily to treat hypertension and angina, and levosulpiride, a substituted benzamide antipsychotic that is also classified as a prokinetic agent for gastrointestinal disorders. - **Amlodipine** blocks L-type calcium channels in vascular smooth muscle, leading to vasodilation and a reduction in blood pressure. - **Levosulpiride** acts as a dopamine D2 receptor antagonist, which provides both antipsychotic effects in psychiatric indications and prokinetic effects in gastrointestinal motility disorders by enhancing gastric emptying and intestinal transit. There is no evidence from the provided search results of a widely marketed or regulatory-approved fixed-dose combination product specifically named "amlodipine + levosulpiride." Both drugs are, however, available and sometimes prescribed together for comorbid conditions, such as hypertension with gastrointestinal symptoms like dyspepsia or GERD, particularly in some countries. Fixed-dose combinations of amlodipine with other cardiovascular drugs, and levosulpiride with other GI medications, are frequently marketed, but there are no widely recognized fixed-branded or generic fixed formulations of this exact combination.

Other names

amlodipine and levosulpirideamlodipine plus levosulpiride