Drug intelligence / Profile preview

amlodipine + losartan

Development stage
Phase 1
Lead developer
Hanmi Pharmaceutical
Modality
Small Molecules
Administration
Oral
01

Overview

Amlodipine + losartan is a combination medication used to treat hypertension. It combines a calcium channel blocker (amlodipine) and an angiotensin II receptor antagonist (losartan). Amlodipine works by dilating blood vessels, while losartan blocks the effects of angiotensin II, a hormone that increases blood pressure. Together, they effectively lower blood pressure by relaxing and widening blood vessels.

Brand names
Amlokind-LLosacar-ACovamloRepace-ATozamZilos-AMNusar-AMAsomex-LT
Other names
amlodipine/losartan
02

Targets

AGTR1 (Angiotensin II Type-1 receptor)LTCC (Voltage-gated calcium channel (L-type))

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