Drug intelligence / Profile preview

amoxicillin + levofloxacin

Development stage
Unknown
Lead developer
Daiichi Sankyo
Modality
Small Molecules
Administration
Oral
01

Overview

Amoxicillin + levofloxacin is a combination antibiotic therapy used primarily for the treatment of Helicobacter pylori infections. This combination is typically administered with a proton pump inhibitor as part of triple therapy regimens. Amoxicillin is a penicillin-type antibiotic that inhibits bacterial cell wall synthesis, while levofloxacin is a fluoroquinolone antibiotic that works by inhibiting bacterial DNA topoisomerase II. The combination provides broad-spectrum coverage against various bacterial pathogens.

Other names
LVX + AMX
02

Targets

DNA gyrasePBP (Penicillin-binding protein family)Topo IV (Bacterial Topoisomerase IV)

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