An'gong Niuhuang Pill

An'gong Niuhuang Pill is a traditional Chinese medicine (TCM) formula that has been used for centuries as an emergency remedy for acute febrile diseases and central nervous system disorders. It is considered one of the most effective formulas in TCM for conditions such as high fever with delirium, coma, stroke, viral encephalitis, and traumatic brain injury. The pill contains a combination of animal-derived and herbal ingredients including Bovis Calculus (cow bezoar), Powdered Buffalo Horn Extract, Artificial Moschus (musk), Cinnabaris (mercuric sulfide), Coptis chinensis Franch., Hyriopsis cumingii (pearl powder), Scutellaria baicalensis Georgi (baikal skullcap root), Realgar (arsenic sulfide), Gardenia jasminoides J.Ellis (cape jasmine fruit), Curcuma aromatica Salisb. (turmeric root), and Borneolum Syntheticum[1][6][8]. Pharmacological studies indicate that the pill exerts anti-inflammatory effects by modulating immune cell infiltration and cytokine production; it also demonstrates hepatoprotective, antiviral, antipyretic/anticonvulsant properties[1][5]. Mechanistically, its active compounds are thought to act on multiple targets involved in oxidative stress response pathways—including IL-6 signaling—and neuroprotection via modulation of inflammatory mediators such as TNF-alpha and AKT1[9]. Modern research supports its use in reducing cerebral infarct size after stroke or traumatic brain injury by protecting neural tissue from inflammation-induced damage[3][4].

Brand names

An'gong Niuhuang PillAngong Niuhuang WanANP

Other names

Angong Niuhuang PillsANW