Drug intelligence / Profile preview

andrographis paniculata + aristotelia chilensis

Development stage
Preclinical
Lead developer
HP Ingredients
Modality
Small Molecules
Administration
Oral
01

Overview

This drug is a **combination of two herbal extracts**: Andrographis paniculata and Aristotelia chilensis. Andrographis paniculata is an annual herb from the Acanthaceae family, standardized to andrographolide, 14-deoxyandrographolide, and neo-andrographolide. It is widely used in traditional medicine for its anti-inflammatory, immunostimulant, antiviral, antibacterial, antidiabetic, and hepatoprotective properties. Aristotelia chilensis is the botanical source of Maqui berry, known for its high content of anthocyanidins (notably delphinidin) and long-standing traditional use for conditions such as sore throat, fever, and inflammation. The combination has been studied for the treatment of common cold and COVID-19-related symptoms, leveraging the immunomodulating and antioxidant activities of both components[1][2][4][5][7].

Brand names
A. PaniculataA. Chilensis
Other names
a. paniculata + a. chilensis
02

Targets

NF-κBNOS2 (Nitric Oxide Synthase 2)

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