antazoline + naphazoline

Allerex is an ophthalmic small molecule combination drug developed and marketed by Lin-Kabs Pharmaceutical. It is primarily indicated for the symptomatic relief of allergic conjunctivitis and minor ocular irritations. The formulation consists of antazoline hydrochloride, a histamine H1 receptor antagonist, and naphazoline hydrochloride, a sympathomimetic alpha-adrenergic agonist. Antazoline works by blocking H1 receptors, thereby reducing allergic symptoms such as itching and swelling. Naphazoline acts as a vasoconstrictor by stimulating alpha-adrenergic receptors on conjunctival blood vessels, which reduces redness and congestion. Allerex is administered topically as an eye drop and is approved for use in managing various inflammatory eye disorders.

Brand names

Allerex

Other names

antazoline/naphazoline