Drug intelligence / Profile preview

arginine + rimantadine

Development stage
Approved
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
Administration
Oral
01

Overview

**arginine + rimantadine** is a combination of two agents administered orally for the prophylaxis and treatment of influenza A virus infection[5][2]. Rimantadine is a synthetic antiviral drug of the adamantane class that inhibits the replication of influenza A viruses by interfering with the viral M2 ion channel, thereby blocking the uncoating of the virus within infected cells[1][2]. Arginine is an amino acid that has been investigated for its ability to inactivate viruses in acidic solution and may enhance antiviral activity through chemical or immunological mechanisms[3]. This fixed-dose combination is intended to potentiate anti-influenza efficacy or modulate viral resistance.

02

Targets

CHRM2 (M2)

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