Drug intelligence / Profile preview

Arrae Bloat + Arrae Calm

Development stage
Unknown
Lead developer
Arrae
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Oral
01

Overview

Arrae Bloat + Arrae Calm is a combination of two commercial dietary supplement products developed by Arrae, designed to address the gut-brain axis by simultaneously targeting digestive discomfort and psychological stress. Arrae Bloat is a botanical blend formulated with Organic Ginger Extract, Organic Dandelion Root Extract, Organic Lemon Balm, Organic Peppermint Leaf, Organic Slippery Elm, and Organic Bromelain (a fruit-based digestive enzyme). It is intended to reduce gas, bloating, heartburn, and symptoms associated with irritable bowel syndrome (IBS) by supporting digestive processes and soothing the gastrointestinal tract. Arrae Calm is a holistic supplement containing four natural ingredients—typically L-theanine, magnesium, passionflower, and ashwagandha—designed to relax the nervous system, alleviate anxiety, and reduce cortisol levels without causing dependency or drowsiness. The combination has been evaluated in a clinical trial (NCT05197413) to assess its efficacy in managing IBS symptoms and stress-related anxiety.

Other names
Arrae Bloat + Calm
02

Targets

GABA-B (Gamma-aminobutyric acid receptor type B)GluR (Glutamate receptors)

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