Drug intelligence / Profile preview

AS900672 + follitropin alfa

Development stage
Unknown
Lead developer
Merck
Modality
Recombinant Proteins and Enzymes
Administration
Subcutaneous
01

Overview

**AS900672 + follitropin alfa** is a combination therapy used in clinical research settings for infertility treatment in women undergoing assisted reproductive technology (ART) procedures. **AS900672** is an investigational long-acting recombinant follicle-stimulating hormone (FSH) analog developed to stimulate ovarian follicular development, while **follitropin alfa** is an approved, recombinant form of FSH produced via recombinant DNA technology, indicated for controlled ovarian stimulation and ovulation induction. The combination may involve starting with AS900672 followed by supplemental follitropin alfa based on ovarian response. Both components act by agonizing the follicle-stimulating hormone receptor, leading to follicular growth and maturation, with the goal of optimizing oocyte (egg) development and increasing the likelihood of successful fertilization and pregnancy in women with infertility[1][2][4].

Other names
recombinant follicle-stimulating hormoneFSHrFSH-alphafollicle stimulating hormone recombinant
02

Targets

FSHR (Follicle-stimulating hormone receptor)

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