Drug intelligence / Profile preview

ascorbic acid + caffeine + glucuronamide

Development stage
Unknown
Lead developer
Bayer
Modality
Small Molecules
Administration
Oral
01

Overview

Guronsan is an over-the-counter (OTC) antiasthenic and detoxifying combination drug containing glucuronamide, ascorbic acid (vitamin C), and caffeine. It is widely used for the symptomatic treatment of temporary fatigue (functional asthenia) and to assist in the elimination of endogenous and exogenous toxins (such as those from alcohol consumption, smoking, or drug intolerances). Glucuronamide acts as a precursor to glucuronic acid, facilitating the glucuronidation pathway in the liver to promote detoxification and excretion of xenobiotics. Ascorbic acid serves as an essential antioxidant and cofactor, helping to replenish vitamin C levels and combat oxidative stress. Caffeine acts as a central nervous system stimulant by antagonizing adenosine receptors, providing an immediate boost in alertness and physical performance.

Brand names
Guronsan
Other names
ascorbic acid + caffeine + glucuronamidecaffeine + ascorbic acid + glucuronamideglucuronamide + ascorbic acid + caffeine
02

Targets

ADORA2A (Adenosine A₂A Receptor)ADORA1 (Adenosine receptor A1 subtype)

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