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aspirin + Chinese herbs (Guangzhou University of Chinese Medicine)
- Development stage
- Unknown
- Lead developer
- Guangzhou University of Chinese Medicine
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
A combination therapy protocol developed by Guangzhou University of Traditional Chinese Medicine for the treatment of acute ischemic stroke. This integrated clinical pathway, evaluated in the PAIS (Clinical Pathway for Acute Ischemic Stroke) Phase 4 trial (NCT00966316), combines conventional Western medicine—specifically aspirin—with Traditional Chinese Medicine (TCM) components, including individualized or standardized Chinese herbal formulations and acupuncture. The protocol is designed to improve clinical outcomes, reduce the length of hospital stays, and lower treatment costs by utilizing the antiplatelet effects of aspirin alongside the multi-target, holistic approach of TCM, which typically aims for neuroprotection and improved cerebral blood flow. The specific herbal formulations used are part of a comprehensive treatment protocol rather than a single named pharmaceutical product.
- Other names
- Clinical Pathway for Acute Ischemic Strokeaspirin + Chinese herbs + acupuncture
02
Targets
TYMP (Thymidine phosphorylase)TBXAS1 (Thromboxane A2 synthase)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)PGHS-1 (Prostaglandin G/H Synthase 1)
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